Quarterly report pursuant to Section 13 or 15(d)

Note 13 - Commitments and Contingencies (Details Textual)

v3.8.0.1
Note 13 - Commitments and Contingencies (Details Textual)
3 Months Ended 9 Months Ended
Oct. 02, 2017
USD ($)
$ / shares
shares
Jan. 01, 2005
shares
Sep. 30, 2017
USD ($)
Sep. 30, 2016
USD ($)
Sep. 30, 2017
USD ($)
ft²
Sep. 30, 2016
USD ($)
Area of Office Space | ft²         7,625  
Operating Leases, Rent Expense, Minimum Rentals         $ 12,522  
Operating Leases, Rent Expense     $ 36,658 $ 25,031 106,828 $ 95,019
Payments for Postemployment Benefits         $ 203,111  
Define Benefit Plan, Payment Period         5 years  
Pension Cost (Reversal of Cost)     51,000   $ 152,000  
Additional Percentage of Director Compensation on Sales Value Using Certain Specify Technology   2.50%        
Additional Percentage of Director Compensation Sales Value Using Other Kind of Technology   5.00%        
Innovest S.p.A. [Member] | Consulting Services [Member]            
Related Party Transaction, Expenses from Transactions with Related Party     20,000   60,000  
Director of Clinical Affairs [Member]            
Stock Issued During Period, Shares, Stock Options Exercised, Attributable to Consultants | shares   8,333        
Royalty Expense     122,606 $ 148,185 446,098 $ 449,875
Professional Fees     $ 68,751   $ 206,253  
Former CEO [Member] | Subsequent Event [Member]            
Employee Resignation Assertion, Basic Salary for One Year $ 300,000          
Employee Resignation Assertion, Health and Disability Insurance for One Year 30,000          
Employee Resignation Assertion, Car Allowance for One Year $ 1,200          
Employee Resignation Assertion, Vesting Term After Resignation 90 years          
Employee Resignation Assertion, Number of Options Vested | shares 921,942          
Employee Resignation Assertion, Options Exercise Price | $ / shares $ 2